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Tampa Bay Buccaneers at Denver Broncos odds, picks and best bets

Esten McLaren
Sportsbook Wire

The Tampa Bay Buccaneers (1-1) take to the road for the second time in the first three weeks, this time do face the Denver Broncos (0-2) at Empower Field at Mile High. Kickoff will be at 4:25 p.m. ET Sunday of Week 3. Below, we preview the Buccaneers-Broncos odds and lines and make our NFL picks and best bets.

Buccaneers at Broncos betting odds and lines

Odds via BetMGM; access USA TODAY Sports' betting odds for a full list. Lines last updated Saturday at 3:30 p.m. ET.

  • Money line : Buccaneers -250 (bet $250, win $100) | Broncos +210 (Bet $100, win $210)
  • Against the spread/ATS : Buccaneers -5.5 (-110) | Broncos +5.5 (-110)
  • Over/Under : 42.5 (O: -110, U: -110)

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Buccaneers at Broncos game notes

  • The Bucs are 1-1 through two NFC South Division games. They lost 34-23 on the road against the New Orleans Saints and beat the Carolina Panthers 31-17 at home.
  • Buccaneers QB Tom Brady has passed for a total of 456 yards with three touchdowns and three interceptions. TE Rob Gronkowski has just two catches for 11 yards.
  • The Broncos are 0-2 straight up but they've lost by just 2 and 5 points and are 2-0 against the spread.
  • Broncos backup QB Jeff Driskel stepped in for an injured Drew Lock to complete 18 of 34 passes for 256 yards, 2 touchdowns and one interception last week against the Pittsburgh Steelers. He'll make his ninth career start this week.
  • Both teams are minus-1 in turnover differential.

Buccaneers at Broncos key injuries

Buccaneers

  • WR Justin Watson (shoulder) out

Broncos

  • QB Drew Lock (shoulder) out
  • RB Phillip Lindsay (foot) doubtful
  • WR Jerry Jeudy (ribs) questionable
  • CB Davontae Harris (hamstring) out

Buccaneers at Broncos: Odds, betting lines, picks and prediction

Prediction

Buccaneers 20, Broncos 14

Money line ( ?)

There's too much chalk on the Buccaneers (-250) to warrant a money line play in Week 3. Their 31-17 win over the Panthers last week was blown open with a late, long TD run by RB Leonard Fournette to make the victory look more convincing than it was.

The Broncos are 0-2 but have proven they can hang around against good teams in the Titans and Steelers. Driskel can do an adequate job of replacing Lock under center, but it's a big ask for him to lead the team many wins, especially with WR Courtland Sutton also suffering a season-ending Week 2 injury.

PASS on the money line and look to the spread.

Against the spread (?)

This line will be tight but the lean is toward the BRONCOS +5.5 (-110). The defense is keeping them in games and Brady has already thrown three interceptions and taken three sacks early in his Bucs tenure.

The Bucs have the healthier and more talented offense, but the Broncos should be able to stick around. Expect a low-scoring game with multiple turnovers on each side keeping the score tight.

Over/Under ( ?)

The UNDER 42.5 (-110) is the top play. Even with WR Chris Godwin returning for the Bucs this week, they're certainly not yet the offensive juggernaut they were expected to be with the additions of Brady, Gronk and Fournette.

There are too many injuries on Denver's side for it to contribute properly to the combined point total.

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